My Discussion With Ziopharm CEO About Unique Genetic Programming Platform

Benzinga recently had the chance to speak with Dr. Laurence Cooper, CEO of Ziopharm Oncology, about the projects and products that Ziopharm is developing. Cooper discussed the company’s latest data on its Sleeping Beauty platform, which Ziopharm project is most exciting and what shareholders should expect in 2016.

Sleeping Beauty Data

Earlier this month, Ziopharm presented exciting data on its Sleeping Beauty platform at the 57th American Society of Hematology (ASH) Annual Meeting. Benzinga asked Cooper about the significance of the data and of the Sleeping Beauty program.

“The question is, why is it that healthy patients get cancer when they have perfectly-functioning immune systems? And the reason is that the programming language, sort of the architecture that your T cells use, has failed you,” he explained.

Whereas other companies use viruses to attempt to “reboot” these T cells, Ziopharm’s platforms allow for direct modification of T cells without the use of a viral intermediary, a process that potentially saves critical time and money.

“Sleeping Beauty is a programming language that you can use to essentially trick the T cells into becoming these killer cells that can recognize tumor cells, and we were able to show that biology at ASH this year” Cooper told Benzinga.

Most Exciting Project

Ziopharm has…

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